Some patients who developed fungal meningitis in an outbreak linked
to a Massachusetts compounding pharmacy are experiencing more health
woes, officials said.
Patients are not only developing
meningitis, inflammation of the thin tissue surrounding the brain and
spinal cord; some are also developing an epidural abscess, which is a
collection of pus between the outer covering of the brain and spinal
cord and the bones of the skull or spine.
Meningitis is a known
complication of an epidural abscess, but what's puzzling some health
experts is that some patients were first diagnosed with and treated for
meningitis and then developed an abscess.
"This is not typical
for fungal disease," says Dr. Tom Chiller, who serves as deputy chief of
the CDC's Mycotic (fungal) Diseases Branch. While he and other health
officials have been hearing about epidural abscesses since the beginning
of the outbreak, it is unclear how many patients have had the
abscesses.
The Centers for Disease Control and Prevention now
lists meningitis, epidural abscess and stroke among the 409 cases of
fungal infection; it also says 10 people have suffered peripheral joint
infections from New England Compounding Center products.
FDA: Drug maker had internal warnings months before outbreak
As
of Monday, the total number of illnesses linked to tainted steroid
injections produced by the NECC had risen to 419. One more person has
died, bringing the total fatalities to 30.
Abscesses are usually
found using an MRI. Some meningitis patients underwent an MRI where no
abscesses were found, and then two or three weeks later, another MRI
detected an abscess after patients reported back pain.
In
Michigan, which has the most illnesses connected to the tainted NECC
medications, nearly half of the patients have developed an abscess.
As
of Monday, the state health department is reporting a total of 119
cases -- 61 cases of meningitis, 51 cases of epidural abscesses, six
peripheral joint infections and one stroke. All seven of Michigan's
deaths were reported in meningitis patients.
All of the epidural
abscesses in Michigan were diagnosed before some patients developed
meningitis, according to Angela Minicucci,Find detailed product
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and other products. spokeswoman for the Michigan Department of
Community health. She says none of the Michigan cases developed
meningitis first and abscesses later.
Tennessee has the
second-highest case count,One of the most durable and attractive styles
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with 79 cases and 12 deaths. However, health officials there have not
yet tallied how many patients had epidural abscesses and when.
The
fungal infection cases are unprecedented, said the CDC's Chiller,
because usually fungal infections caused by black mold usually trigger
sinusitis or skin infections -- the fungus isn't injected into the
central nervous system with a steroid.
"We're learning as we go,Thank you for visiting! I have been cry stalmosaic since 1998." he says, adding that patients are presenting with illness in completely new ways.
Feds open criminal inquiry into firm linked to outbreak
According
to the CDC, symptoms have appeared between one and four weeks after an
injection. Since the NECC products were recalled just about a month ago,
one would think that window would be closing.
But given that
some patients are developing secondary infections such as abscesses and
others are reporting symptoms after longer periods of time, Chiller says
patients need to be vigilant for at least several months.
Bottom
line: If patients know they've been given injections from the three
tainted lots of the preservative-free steroid methylprednisolone acetate
(MPA) distributed by NECC, they need to see their doctor with any new
symptoms or concerns.We have a wide selection of dry cabinet to choose from for your storage needs.
In the meantime, lawmakers are continuing to look for answers about how the outbreak occurred.
On
Monday, the House Energy and Commerce Committee announced that the
Subcommittee on Oversight and Investigations will convene a hearing on
November 14 to further investigate what went wrong at the NECC and why
the company, which had a history of problems, was able to continue to
function.
Food and Drug Administration Commissioner Margaret
Hamburg is scheduled to testify. James Coffey, director of Massachusetts
Board of Registration in Pharmacy, and Barry Cadden, owner and director
of the New England Compounding Center, have also been
invited.Purelink's real time location system protect healthcare workers in their daily practices and OMEGA interventions.
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